McCormick Science Institute Antioxidant and Weight Managment Properties of Cinnamon Extract
Print This PagePrint This Page Decrease Font SizeIncrease Font Size Type Size Email This PageEmail This Page
Research Highlights Find More Research

August 2009-- Dr. Roussel and others at the Université Joseph Fourier in France looked at the effects of a cinnamon extract on vascular health and blood glucose in overweight subjects. Read the entire study (PDF)

cinnamon_antioxidant

Antioxidant and Weight Management Properties of Cinnamon

Roussel AM, Hiniger I, Benaraba R, Ziegenfuss TN, Anderson RA

Objective

To determine the effects of a dried aqueous extract of cinnamon on antioxidant status of people with impaired fasting glucose that are overweight or obese.

Methods

Twenty-two subjects, with impaired fasting blood glucose with BMI ranging from 25 to 45, were enrolled in a double-blind placebo-controlled trial. Subjects were given capsules containing either a placebo or 250 mg of an aqueous extract of cinnamon (Cinnulin PF) two times per day for 12 weeks. Plasma malondialdehyde (MDA) concentrations were assessed using high performance liquid chromatography and plasma antioxidant status was evaluated using ferric reducing antioxidant power (FRAP) assay. Erythrocyte Cu-Zn superoxide (Cu-Zn SOD) activity was measured after hemoglobin precipitation by monitoring the auto-oxidation of pyrogallol and erythrocyte glutathione peroxidase (GPx) activity by established methods.

Results

FRAP and plasma thiol (SH) groups increased, while plasma MDA levels decreased in subjects receiving the cinnamon extract. Effects were larger after 12 than 6 weeks. There was also a positive correlation (r = 0.74; p = 0.014) between MDA and plasma glucose.

Conclusion

This study supports the hypothesis that the inclusion of water soluble cinnamon compounds in the diet could reduce risk factors associated with diabetes and cardiovascular disease.

Reference

Roussel AM, Hininger I, Benaraba R, Ziegenfuss TN, Anderson RA. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr. 2009 Feb;28(1):16-21. Read the entire study (PDF)

 

 

 

Research Area

Inflammation

In Vitro Study on Spices and Blood Glucose (Aug, 2009)

Inhibition of protein glycation by extracts of culinary herbs and spices.

Inflammation

MSI Funded Research: Effects of Antioxidant-rich Spice Added to Hamburger During Cooking (Jun, 2010)

A study that looked at the consumption of a spice enriched burger on malondialdehyde (MDA) levels. The study found that subjects who consumed the spice burger had lower plasma and urine MDA levels than when they consumed the non-enriched burger. The spice mixture added to hamburger meat before cooking also reduced malondialdehyde concentrations in the burger itself as compared to the burger cooked without spices.

PubMed MOPS top test

Keyword(s):
Use AND, OR and NOT, and multiple keywords to help refine your search.

Multi-Select
Interested in a broad range of research on spices, herbs and health? Select the spices, research area and/or health topics of interest to you from the pulldown menus by holding down the control key (Windows) or the command key (MAC) as you click.

Select Spice/Herb(s):

Select Research Area:

Select Health Topic(s):